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September 3, 2026

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UniQure is breathing a sigh of relief after its controversial gene therapy for Huntington’s disease successfully cleared a critical regulatory hurdle. The company has faced an uphill battle with skeptics and setbacks, making this latest milestone a pivotal moment for both the organization and the patient community awaiting a viable treatment for the devastating neurodegenerative condition.

The path toward approval has been fraught with tension, as researchers worked to prove that their approach could safely target the genetic root of the disease without causing adverse effects. By meeting these key requirements, UniQure has effectively silenced some of the loudest critics who questioned whether the therapy was ready for wider application. This breakthrough suggests that the technical challenges which previously plagued the project are finally being resolved.

Industry analysts view this development as more than just a corporate win; it represents a glimmer of hope for families affected by Huntington’s, a hereditary disorder that currently lacks a cure. While there is still work to be done before the therapy reaches general clinical availability, clearing this obstacle removes one of the most significant roadblocks in the drug’s developmental timeline.

As UniQure moves forward into the next phase of testing and validation, investors and medical professionals alike will be watching closely to see if early promise translates into long term efficacy. If successful, this therapy could redefine how doctors treat rare genetic diseases, turning what was once considered an impossible task into a scalable medical reality.

Swiss banking giant UBS has downgraded its outlook on the Spanish construction firm Ferrovial, shifting the stock from a buy to neutral following the company’s aggressive pursuit of a massive toll lane project in Tennessee. The decision stems from concerns over the financial risks associated with the DriveTN consortium’s winning bid for improvements to I-24, I-440, and I-40 around Nashville. According to UBS analysts, Ferrovial may have lacked discipline during the bidding process, promising the state nearly 25 billion dollars in concessions that far exceed those offered by any other competitor.

The disparity between the bids is stark. While two other firms offered roughly 7 billion dollars in payments and one actually requested a government subsidy, DriveTN pledged a staggering sum, including 1.5 billion dollars upfront. This boldness earned them praise from Governor Bill Lee, who highlighted how these funds could support other critical infrastructure across the state. However, UBS warns that such a heavy upfront commitment combined with significant early debt could lead to an underwhelming equity return of just seven percent, which they argue does not justify the level of risk involved.

This financial skepticism has already reached Capitol Hill in Nashville, where some legislators are voicing alarm. Representative Vincent Dixie expressed concern that taxpayers might eventually be left footing the bill if the project falters, questioning why a corporation of Ferrovial’s size would commit so many billions without a safer margin for error. He described both the gap in competing bids and the subsequent stock downgrade as significant warning signs regarding the viability of the long term agreement.

Despite these warnings, Tennessee transportation officials maintain there are no red flags concerning the partnership. State leaders remain focused on the potential for rapid modernization and immediate revenue influxes provided by Ferrovial and its partners at Cintra and Transurban. For now, UBS intends to monitor further developments on this project as well as another similar venture in Atlanta before reconsidering its stance on Ferrovial’s stock value.

Wall Street saw a modest boost on Wednesday as the Dow Jones Industrial Average and other major indices managed to hold onto steady gains. Investors were primarily reacting to new employment figures that came in weaker than expected, a surprise that shifted the mood of the trading day. This labor market shift helped stabilize benchmark Treasury yields, providing some breathing room for equities across the board.

Small cap stocks led the charge in terms of performance, outperforming their larger counterparts throughout the session. Within the blue chip space, Caterpillar showed signs of recovery, appearing poised to snap a frustrating four day losing streak. By the time late afternoon trading rolled around, the Dow had climbed more than 250 points as buyers stepped back into the market.

Meanwhile, individual corporate movements continued to draw significant attention from traders. Dell remained a focal point as it attempted to break out of its current range, joining several other tech names like Credo and Palo Alto Networks as key movers following recent earnings reports. While broader questions about the health of the long term uptrend persist, today’s action suggested a temporary win for bulls fueled by shifting economic data.

Broadcom shares took a dip during recent trading sessions despite reporting fiscal third quarter results that managed to beat analyst expectations across several key metrics. While the company showed strong growth and resilience in its core operations, investors seemed less impressed by the numbers than one might expect from a positive earnings report. This reaction highlights a common trend in today’s volatile tech market where meeting goals is often not enough to satisfy shareholders who have already priced in aggressive optimism.

The decline suggests that much of the good news was likely anticipated by the market well before the official announcement. In many cases, when a stock falls after beating estimates, it indicates a sell the news mentality among traders who had bought into the hype leading up to the release. Investors may also be scrutinizing forward looking guidance more closely than current wins, questioning whether Broadcom can maintain its momentum amidst shifting demand for artificial intelligence infrastructure and semiconductor hardware.

Market analysts suggest that broader macroeconomic pressures could also be playing a role in the price drop. With fluctuating interest rates and global supply chain uncertainties still lingering in the background, some institutional investors may be taking profits rather than doubling down on high flying chip stocks. Even though Broadcom remains a powerhouse in connectivity and software solutions, it is currently navigating a landscape where perfection is expected and anything slightly short of spectacular leads to immediate corrections.

Wall Street appears to be catching its breath after a volatile stretch, with stock futures remaining largely flat Wednesday evening. This quiet period follows a relief rally during the regular session where the major indexes finally broke a three day losing streak. The Dow Jones Industrial Average led the charge with a gain of nearly 300 points, while both the S&P 500 and Nasdaq Composite managed modest climbs of half a percent.

The recent turbulence was primarily fueled by geopolitical tensions between the United States and Iran, combined with a sharp spike in Treasury yields. Investors watched nervously as the two year Treasury yield hit levels not seen since early 2025, reflecting deep concerns over inflation and instability. However, some optimism remains rooted in fundamental economic strength. John Williams, President of the New York Federal Reserve, suggested that these rising yields might actually reflect confidence in a robust U.S. economy driven by massive investments in artificial intelligence and data center infrastructure rather than purely negative financial pressures.

While indices stabilized, individual company movements provided plenty of drama in after hours trading. Snowflake saw its shares surge more than 20 percent after delivering second quarter results that comfortably beat analyst expectations. In contrast, chipmaker Broadcom experienced a rocky ride; its stock initially plummeted five percent following an earnings report that missed slightly on revenue forecasts before eventually clawing back toward break even territory. Other notable shifts included a jump for Petco on stronger margins and a slip for Hewlett Packard Enterprise despite positive long term guidance.

Looking ahead, market participants are shifting their focus toward critical labor data to gauge the health of the broader economy. All eyes will be on Thursday’s weekly jobless claims and Friday’s highly anticipated August payrolls report. With several high profile earnings calls scheduled for Thursday including those from Ciena and Campbell’s, traders will likely remain cautious until there is clearer direction on whether the current recovery can hold against the backdrop of ongoing international conflict.

While the world remains obsessed with the race for faster chips and smarter algorithms, Bruce Kahn believes we are overlooking a far more primitive obstacle. In a recent discussion regarding the AI boom, Kahn, a senior portfolio manager at Shelton Capital Management and lecturer at Columbia University, argued that the true ceiling for artificial intelligence isn’t found in silicon, but in the wires. According to Kahn, the industry has already hit a critical bottleneck where the demand for compute power has far outpaced the ability of existing electrical grids to provide power and cooling systems to manage the heat.

This physical limitation comes at a time when Kahn questions whether the financial foundations of AI are as solid as they appear. He suggests that much of the current frenzy is driven by circular capital flows rather than organic revenue from end users. Pointing to massive capital expenditures from giants like Meta and Alphabet, Kahn notes that spending is currently outrunning genuine income. He warns that some of the perceived demand is inflated by complex arrangements where chipmakers take stakes in startups that then use that money to buy more chips, creating an illusion of growth that lacks traditional market validation.

To cope with these shortages, tech giants are experimenting with temporary fixes like leased jet turbines and onsite solar arrays. However, Kahn views these as mere stopgaps. For AI to truly scale, he argues there must be a return to large scale centralized power, predicting that nuclear energy will play a far more significant role than renewables due to the sheer volume of electricity required. This shift toward heavy infrastructure highlights a sobering reality: no matter how advanced an AI model becomes, it cannot function without a stable plug in the wall.

Beyond the technical hurdles, Kahn observes a dangerous intersection between infrastructure needs and an overflow of private credit. He describes data centers as becoming a de facto receptacle for vast amounts of investor capital searching for any available home. With fund managers eager to deploy dry powder into trending sectors, there is a rising risk that capital is flowing into lower tier projects regardless of their viability. Ultimately, Kahn sees AI not as one seamless trend, but as several colliding forces—technological ambition meeting old fashioned industrial limitations and aggressive financial speculation.

In a strategic overhaul of its national wealth, De Nederlandsche Bank has completed the movement of over 10 billion euros in gold reserves away from North American vaults. Between March and August 2026, the Dutch central bank shifted approximately 86 tons of gold out of facilities in New York and Ottawa, redistributing the assets between London and the Netherlands. This maneuver significantly boosts the country’s presence at the Bank of England, which serves as the world’s premier hub for bullion trading, increasing their holdings there from 18.1 percent to 32.1 percent of their total reserves.

The process involved a mix of logistical shipping and clever market maneuvers to avoid unnecessary costs. To ensure the metal met modern international trade standards without needing to be melted down, the bank sold about 59 tons of gold in New York and immediately repurchased an equivalent volume in London. Meanwhile, another 27 tons were physically transported back home to the DNB Cash Centre in Zeist. While these shifts changed where the gold is kept, they did not change how much the country owns; the Dutch gold reserve remains steady at 612.4 tons, with a valuation reaching 72.2 billion euros by late 2025.

Governor Olaf Sleijpen explained that the move was primarily designed to improve the tradability of these reserves and bolster national resilience. He noted that while he expects the government will never actually need to tap into these stores, being prepared is essential for economic security. This shift reflects a broader trend among global financial institutions toward more active portfolio management and domestic custody. According to World Gold Council data, nearly half of all central banks actively managed their reserves in 2025, with many opting to bring precious metals closer to home or into high-liquidity hubs like London.

The Netherlands is not alone in this cautious approach to asset management across Europe. In recent months, Banque de France conducted a similar swap by selling billions in New York-held gold to repurchase it for storage in Paris, while Germany continues to face political pressure to repatriate massive amounts of gold currently held at the U.S. Federal Reserve. These movements come during a period of soaring value for the yellow metal, with some analysts forecasting prices could climb as high as 6,000 dollars per ounce by next year as nations continue to seek safe-haven assets amidst global uncertainty.

A New York prosecutor accused state Attorney General Letitia James’ office of directing employees to “find and pursue crimes” involving President Donald Trump and entities tied to him, according to a report.

The allegation stems from an email sent by Assistant Attorney General Daniel Wiesenfeld, who works in the Investor Protection Bureau of the New York Office of the Attorney General, which is led by Shamiso Maswoswe, the Times Union reported. The email was allegedly later wiped from the office’s servers, according to the outlet, while James’ office dismissed the matter as a personnel issue and rejected claims that the office was targeting people based on political beliefs.

Wiesenfeld alleged that Maswoswe directed him to target “Trump himself, Truth Social, Hewlett Packard (DOJ approved merger)… without having a credible reason for targeting [these] organizations and individuals,” according to the Times Union.

Maswoswe previously worked as a trial attorney in the Justice Department’s Public Integrity Section from January 2016 until her termination in December 2017, under Trump’s first term. In February 2021, she filed a discrimination lawsuit against the Justice Department, alleging she was unfairly terminated and subjected to discrimination based on her race, pregnancy and caregiving responsibilities.

TRUMP’S LAWYERS PUT DEM AG ON NOTICE FOR TARGETING HIS FAMILY IN NY FRAUD FIGHT: ‘CANNOT STAND’

Wiesenfeld reportedly sent an agency-wide email to colleagues Friday with instructions “to find and pursue crimes committed by specific individuals and organizations affiliated with Donald Trump,” the Times Union reported.

The email reportedly was then allegedly wiped from servers, with a subsequent email sent from James’ general counsel, Kumiki Gibson, informing employees that it was an “internal” matter and no employees were “in danger,” the Times Union reported.

“This is a personnel matter. The Office of the Attorney General is committed to upholding New York’s laws and protecting the rights and freedoms of all New Yorkers, regardless of political beliefs. We strongly reject any assertion to the contrary,” a spokesperson for the Office of the New York Attorney General told Fox News Digital.

The New York Post reported Wiesenfeld was placed on paid administrative leave.

“This is more proof of the weaponization of the justice system by Letitia James to target President Trump and her political opponents. The far-left Democrats lawfare against President Trump, his family, and allies must stop,” White House spokesperson Lauren Bis told Fox News Digital.

Before Maswoswe joined James’ office in February 2022, she filed a discrimination suit against the DOJ.

LETITIA JAMES HAMMERED AFTER NY MEDICAID FRAUD UNIT FUNDING FROZEN OVER INEFFECTIVE ENFORCEMENT

She filed a complaint in February 2021 alleging she was unfairly fired during the Trump administration in 2017 and discriminated against for being Black and having a child.

Maswoswe accused the DOJ of race discrimination due to her Zimbabwean descent and was scrutinized over her pregnancy, breastfeeding and caregiving responsibilities – seeking reinstatement, back pay and damages, according to court docs.

In 2023, the two parties reached a settlement with Maswoswe, awarding her $795,000 to resolve all claims related to her employment and lawsuit. 

DOJ expressly denied that Maswoswe’s claim were true and the agreement says the payment was a compromise of disputed claims – not an admission that discrimination or retaliation occurred.

James has been a longtime critic and legal adversary of Trump, launching a civil fraud lawsuit against him and the Trump Organization in 2022 after campaigning on investigating his business practices.

The case initially resulted in more than $450 million in penalties, though an appeals court later upheld Trump’s liability while voiding the financial penalty.

DETROIT — A propaganda newspaper that once accepted a massive grant from George Soros’ Open Society Foundation falsely described beleaguered leftist Michigan U.S. Senate candidate as a veteran, according to a copy of that paper obtained by Fox News Digital.

“El-Sayed — veteran, doctor, and former health official — is Democratic Senate pick,” reads a headline in the August 2026 edition of The Michigan Independent.

The papers were distributed in Michigan, and photos of the headline made the rounds on social media last week. The breadth of the paper’s circulation is unclear, but Fox News Digital obtained a physical copy in Michigan.

LIZ PEEK: MICHIGAN CAN STOP THE SOCIALIST FEVER RAGE — OR WATCH IT SWALLOW THE SENATE

The purportedly independent paper circulating in Michigan has a Washington, D.C. non-profit’s name and address — The American Independent Foundation at 800 Maine Ave SW — emblazoned in the bottom left corner of the front cover.

As it turns out, the papers aren’t independent at all.

TOP MEDIA OUTLETS FAIL TO DISCLOSE WHO IS BANKROLLING THEIR AI REPORTERS

In 2024, The American Independent Foundation, a 501(c)(3) tax-exempt organization, received a $500,000 grant from George Soros’ Foundation to Promote Open Society, according to that organization’s IRS 990 disclosure form.

Soros, a billionaire businessman, investor and philanthropist, is a renowned leftist mega donor known for his support of progressive and Democratic causes. The Washington Free Beacon first reported the Soros connection.

The content of the Michigan Independent story mentions nothing of El-Sayed being a veteran, nor does it clarify that while El-Sayed holds an M.D., he has never been a physician.

El-Sayed’s campaign forcefully condemned the publication’s classification of the candidate.

“Abdul has never claimed to be a veteran, he never would out of his respect for those who served, and any outlet or group writing about our campaign should do their homework and not allow this to happen again,” spokesman Cole Wozniak told Fox News Digital.

The American Independent did not return Fox News Digital’s request for comment.

JONATHAN TURLEY: FAKE POLLSTER’S STUNT WAS A RECKLESS GAME WITH REAL RACES

Twelve other state-based newspapers are part of the network Soros helped fund, including papers in key swing states like Ohio, Pennsylvania, Wisconsin, Virginia and others that have become increasingly important in the 2026 midterms due to competitive U.S. Senate races, including Maine and Alaska.

Some of the outlets share the same featured stories. At the time of this writing, both The Ohio Independent and The Pennsylvania Independent feature a story titled “Report: Trump and Big Oil see financial windfall as Americans pay more at pump”.

SOROS NETWORK REBUILDS PROGRESSIVE PROSECUTOR PUSH AFTER STRING OF ELECTION LOSSES

An associated 501(c)(4) political activism organization, American Independent Media, is also affiliated with the network of news outlets. Each state-based website says it is a project of American Independent Media whose mission is “to use journalism to educate the public, giving them the information they need about local and federal issues.”

David Brock, founder of the far-left media watchdog Media Matters and a high-profile Democratic operative, is also connected to the shadowy network of papers.

He is the founder of the 501(c)(3) American Bridge, also a titan in left-wing politics. American Bridge’s 501(c)(4) arm, the AB Foundation, donated $23.5 million to American Independent Media in 2024.

DEM SENATE HOPEFUL’S ‘PHYSICIAN’ CAMPAIGN PITCH UNDER FIRE AFTER LICENSE RECORDS REVEAL KEY GAPS

The story about El-Sayed was penned by Alyssa Burr, whose LinkedIn page says she’s the Michigan Politics Reporter at The American Independent.

She previously worked at MLive Media Group, which publishes prominent state newspaper Michigan Live, and before that, the New York Times.

President Donald Trump revived speculation over regime change in Iran Tuesday night, openly asking when Iranians would “rise up and fight” as his administration intensified military and economic pressure on a government US officials say is increasingly vulnerable.

“I’m not trying to force Iran to the bargaining table,” Trump wrote on Truth Social Tuesday. “I like our position now much better, with almost total control of the Hormuz Strait, and their economy totally collapsing.”

“They are just playing out the inevitable,” Trump added. “When are the Iranian people going to rise up and fight?”

IRAN REGIME CHANGE TALK RESURFACES AS TRUMP SAYS TEHRAN ‘WANTS TO MEET’ AMID US STRIKES

Trump sharpened those remarks later Wednesday when Fox News’ Peter Doocy asked whether he would send the CIA to arm Iranians if he wants them to “rise up and fight.” 

“I’d love to tell you that, but it wouldn’t be appropriate to say,” Trump responded from the Oval Office.

Trump said he understood why Iranians have not risen in larger numbers, arguing that protesters face deadly repression from the government. 

“Most people can’t kill their own people like that. Most people try and reason when they talk. And then there might be an overthrow. In Iran, they kill people. … They shoot them right between the eyes. They have two forms: machine guns and snipers. … They like the snipers better because all they do is have a crowd of 200,000 people, and a person goes down here right between the eyes, and they’ll have three snipers doing it. And, it’s a horrible thing to watch,” he said. 

“So that’s why it’s not happening,” the president added, “And who can blame them? Who can blame them? But the regime is getting weaker by the day… And at some point, they’re not going to be able to shoot so easily because I think the people aren’t going to take it,” Trump said. “But I did pose that question because, you know, it would be time.”

COULD IRAN’S REGIME COLLAPSE? EXPERTS ASSESS BESSENT’S BID TO SEVER FINANCIAL LIFELINES

Treasury Secretary Scott Bessent described Iran as being in a “death spiral” during remarks Monday, arguing that economic pressure was rapidly narrowing the government’s options.

“They are panicked. They are resorting to kinetic because they are getting squeezed economically,” Bessent told Ed Lawrence on Fox Business.

Bessent said Iran could eventually face one of three outcomes: “Either the IRGC are going to turn on each other, the people are going to turn on them, or they are going to come to the table and want to do a deal that they can stick with.”

“They are in the death throes,” he added, comparing Iran’s deterioration to bankruptcy occurring “slowly, then quickly.”

Miad Maleki, a senior fellow at the Foundation for Defense of Democracies and former Treasury sanctions official, told Fox News Digital that Washington does not need to choose between invading Iran to overthrow the government and striking another agreement with Tehran.

“It’s very clear U.S. government is not in the business of regime change anymore,” Maleki said. “And I think it’s very clear that we’re not going to have boots on the ground to invade Iran. And I don’t think we need that.”

INSIDE TEHRAN: IRANIANS DESCRIBE IRGC’S BRUTAL RULE, POVERTY — ASK TRUMP TO ‘STAY THE COURSE’

Instead, Maleki argued Washington should “contain this regime, cut off its economic lifelines, empower the Iranian people” and prepare for another wave of demonstrations inside Iran.

“We need to be prepared to support the Iranian people in a way that they can be empowered and take the government back,” he said, stressing the importance of ensuring protesters maintain access to the internet so they can communicate, mobilize and make their voices heard.

Maleki described Iran’s leadership as the weakest it has been since the 1979 Islamic Revolution and argued that further Iranian military escalation could deepen its vulnerability rather than restore lost leverage.

The debate comes as reports of localized economic protests continue to emerge from inside Iran.

TRUMP SAYS IRAN IS ‘DEAD’ — EXPERTS POINT TO THE REAL SIGN TEHRAN IS NEARING THE BRINK

The National Council of Resistance of Iran, an exiled Iranian opposition coalition, said Tuesday that workers, retirees, drivers and job-seeking young people demonstrated in several cities on Aug. 31. The group alleged security forces opened fire on job seekers in Gachsaran and Ahvaz and reported separate demonstrations over unpaid wages, inflation, fuel shortages and working conditions. Those specific claims have not been independently verified by Fox News Digital.

Iran analyst Benny Sabti also told Fox News Digital that deteriorating living conditions could become a catalyst for broader unrest. “People are hungry,” Sabti said, predicting Iranians would “take the streets again.”

“Hunger is humiliating,” he said, arguing that economic desperation could eventually outweigh fear of the government’s security apparatus.

The political stakes are rising alongside a dramatic military escalation. US forces carried out another wave of strikes Tuesday against Iranian air-defense systems, radar installations, maritime assets and mine-laying capabilities, according to US Central Command, while Iran retaliated with missile and drone attacks against US assets across the region.

For Trump, however, Tuesday night’s post suggested the question may no longer be only whether economic pressure brings Tehran back to negotiations — but what happens inside Iran if it does not.